Columbus is a science laboratory that is part of the International Space Station (ISS) and is the largest single contribution to the ISS made by the European Space Agency (ESA). Like the Harmony and Tranquility modules, the Columbus laboratory was constructed in Turin, Italy by Rome based Thales Alenia Space with respect to structures and thermal control. The functional architecture (including software) of the lab was designed by EADS in Bremen, Germany where it was also integrated before being flown to the Kennedy Space Center (KSC) in Florida in an Airbus Beluga.